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Bruce Rubin, MEngr, MD, MBA, FRCPC

Professor of Pediatrics

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Pulmonary medicine

Board Certifications

Pediatrics, Pediatric Pulmonology, Fellow of the Royal College of Physicians and Surgeons of Canada


Children's Pavilion
1000 East Broad Street
Richmond, VA 23219
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Areas of interest

Mucus clearance disorders
The technology-dependent child
Aerosol therapy
Rare lung diseases
Severe Asthma
Chronic cough
Plastic bronchitis


Dr. Rubin served as Jesse Ball DuPont Distinguished Professor and Chair of the Department of Pediatrics from 2009 - 2020 and Physician in Chief of the Children’s Hospital of Richmond at VCU from 2010-2020. He is also a Professor in the VCU College of Engineering and Adjunct Professor of Physiology and Biophysics. Dr. Rubin came to VCU after 12 years at Wake Forest University in Winston-Salem, N.C., where he was professor and vice chair for research in the pediatrics department. He has been named a Virginia Eminent Scholar in Pediatrics.

Dr. Rubin received his undergraduate Bachelor of Science in math and physics, Master of Engineering and Medical degrees from Tulane University in New Orleans. He is a Rhodes Scholar, and conducted postdoctoral work in biomedical engineering at Oxford University. He also earned an MBA at Wake Forest University. He is a member of Board of the Virginia March of Dimes, The Virginia Board of Health Professions, the VCU Center for Communication and Health, the International Congress of Pediatric Pulmonology (CIPP), and the American Respiratory Care Foundation, and he is Medical Advisor to the Virginia Society of Respiratory Care. He is a fellow of the American Academy of Pediatrics and of the Royal College of Physicians and Surgeons of Canada.

Dr. Rubin received the Forest Bird Lifetime Scientific Achievement Award as well as the Jimmy A. Young Medal from the AARC, the Prix extraordinaire from CIPP and he is a Prix Galien Laurate. He holds honorary appointments in four medical schools, is on the editorial board of 11 journals, has published more than 300 original research papers and chapters, and holds 10 patents. His research focus is regulation of mucus clearance in health and disease, airway inflammation and immunomodulation, cough and aerosol delivery of medications.

Dr. Rubin is also a magician, elected to membership in the International Brotherhood of Magicians (Wizard Award) and over the past 25 years has taught medical magic in 40 countries on 5 continents.


Education BS: Tulane University (math and physics)<br>MS: Tulane University (biomedical engineering) <br>MBA: Wake Forest University, Babcock School of Business<br>Rhodes Scholar, Oxford University, England
Medical School Tulane University School of Medicine
Residency Tulane University and The Hospital for Sick Children, Canada
Fellowship The Hospital for Sick Children

Research interests

Airway inflammation - We study relationships among inflammatory cells and mediators, infection, mucus secretion, and quality of life; and the mechanisms causing squamous metaplasia and goblet cell hyperplasia. We develop and test new therapies from cell and tissue culture, to animal studies, to clinical trials. Secretory hyperresponsiveness - Excessive mucus secretion is characteristic of diseases like asthma, COPD, cystic fibrosis, middle lobe syndrome and plastic bronchitis. We study the mechanisms of secretory hyperresponsiveness, characterize the biophysical and transport properties of mucus, and evaluate new therapies with collaborators from around the world. We maintain the International Registry for Plastic Bronchitis. Nasal and sinus disease - We have studied the physical and transport properties of mucus and sputum for three decades. We have formed a sino-nasal research group with investigators from the Rubin lab and the departments of Ear, Nose and Throat, Allergy, Radiology, Nursing, Emergency Medicine and the School of Engineering to develop new ways to measure the impact of sinus disease and test new therapies including novel aerosol delivery systems.

Ratings & reviews

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Related videos

Cough in the time of COVID-19 - Bruce Rubin, MEngr, MD, MBA, FRCPC
  • Specialty: Pediatric Pulmonary Medicin

Board Certifications

Clinical Interests

  • Mucus clearance disorders
  • The technology-dependent child
  • Aerosol therapy
  • Rare lung diseases
  • Severe Asthma
  • Chronic cough
  • Plastic bronchitis

Provider Videos

  • Cough in the time of COVID-19 - Bruce Rubin, MEngr, MD, MBA, FRCPC